BIOMED (BME)

University Directory
University Courses

BME 798 MASTER'S THESIS
Credit to be arranged; not to exceed 6 credits toward fulfillment of M.S. degree requirements. Open only to students pursuing the M.S. thesis option. Supervised original or expository research culminating in an acceptable thesis. Oral defense findings are required. This course will be the basis for the student’s thesis required in partial fulfillment of the requirements for the master of science degree in the Biomedical Engineering program.

BME 604 SENSING AND SIGNAL PROCESSING
BME 604 SENSING AND SIGNAL PROCESSING (3-0) 3 credits. Presentation of principles, characteristics, and applications of instrumentation systems including, sensors, filters, instrumentation amplifiers, analog-to-digital and digital-to-analog conversions, and noise. This course will be useful to graduate students beginning their laboratory thesis research. It is available to students from other departments with permission of instructor.

BME 601 BIOMATERIALS
(3-0) 3 credits. This course will provide students with an overview of the field of biomaterials with the knowledge necessary to conduct biomedical product development and/or biomaterials research. The first portion of the course will provide an introduction to the major classes of materials used in medical devices including metals, polymers, ceramics, composites, and natural materials. Topics covered will include material properties, material processing, testing, corrosion, biocompatibility, tissue responses, etc. The second portion of the course will cover specific biomaterial applications such as dental, orthopedic, cardiovascular, drug delivery, and tissue engineering. The topics of implant cleanliness and sterilization methods will also be discussed. In addition, the topic of national and international governmental regulations and requirements will be reviewed including examples of investigative devices exemptions and 510k submissions.

BME 602 ANATOMY AND PHYSIOLOGY FOR ENGINEERS
(3-0) 3 credits. Introduces biomedical engineering students to fundamentals of human anatomy and physiology. Topics include engineering anthropometry, the skeletal system, skeletal muscle, the neuromuscular control system, the respiratory system, the circulatory system, the metabolic system, the thermoregulatory system, body rhythms, and an introduction to reengineering the human body.

BME 724 BIOPOLYMERS
(3-0) 3 credits. This course is to survey the structure, function, properties and use of biopolymers. The course has three fifty minute lectures per week on Monday, Wednesday and Friday. Supporting reading materials will be assigned from the textbook and supplementary reading materials (see the list above). Please note that the textbook is meant to supplement the lectures, not to substitute for them; you will ONLY be responsible for the materials presented in the lectures.

BME 725 BIOCOMPOSITES
(3-0) 3 credits. This course focuses on composite materials applied to bioengineering. First part of the course introduces biocomposites for medical applications and biocompatibility. Second part focuses on mechanical design and manufacturing aspects of various fibrous polymer matrix composites in terms of: i) material selection, fabrication, and characterization, ii) mechanics of composite materials, iii) design with composite materials. Third part deals with ceramic or nano composites and their applications in biomedical engineering. Final part introduces various case studies such as dental, orthopedics, prosthetic socket, and external fixator applications.

BME 726 BIOCOMPOSITES BIO/MEMS AND NANO SYSTEMS
(3-0) 3 credits. Course Description: Application of microelectromechanical systems (MEMS) and nano-systems to biological systems, interaction of living cells and tissues with MEMS substrates and nano-engineered materials, microfluidics, engineering of inputs and outputs.

BME 731 ADVANCED BIOMECHANICS
(3-0) 3 credits. The course presents the fundamentals of continuum mechanics and nonlinear theory of elasticity with applications to the mechanical behavior of soft biological tissues.

BME 732 MEDICAL IMAGING
(3-0) 3 credits. This course covers the physics of the major modalities commonly used in medical imaging. Also covered are the various principles and methods of constructing an image from the physical interactions of energy with living tissue, and the influence on image quality of the different modalities. Medical imaging systems to be analyzed include conventional X-ray, computed tomography (CT), magnetic resonance imaging (MRI), nuclear medicine (PET and SPECT), and ultrasound. Each of these modalities will be introduced from basic physical principles to the process of image formation. The primary focus is on the physical principles, instrumentation methods, and imaging algorithms; however, the medical interpretation of images, and clinical, research and ethical issues are also included where possible to give students a deeper understanding of the medical imaging field.

BME 733 CARDIOVASCULAR FLUID DYNAMICS
(3-0) 3 credits. Mechanics of blood circulation, fluid mechanics of the heart, blood flow in arteries, unsteady flow in veins, current concepts in circulatory assist devices, biofluidics, and other selected topics. Review of cardiovascular physiology; introduction to fluid mechanics; Models of blood flow and arterial wall dynamics; Fluid mechanics and arterial disease; heart valve fluid dynamics; Ventricular assist devices.

BME 734 TRANSPORT PHENOMENA IN BIOMEDICAL ENGINEERING
(3-0) 3 credits. The study of transport phenomena in biomedical systems including analysis of engineering and physiological systems and incorporation of these principles into the design of such systems. The objective of this course is for students to learn to think about, understand and model the dynamic behavior of complex biological systems. The scope of the systems to be studied is restricted to an analysis of biotransport phenomena in the human body.

BME 735 CAD/ CAM IN MEDICINE AND SURGERY
(3-0) 3 credits. Introduction to computer aided design and modeling of prosthetic devices, and their subsequent manufacture using computer aided manufacturing techniques. Applications in orthopedic implant design and fabrication, dental implant design and fabrication, as well as other types of prosthetics. An advanced level review of current computer modeling and manufacturing technology for medical applications.

BME 737 ADVANCED SIGNAL PROCESSING AND IMAGING
(3-0) 3 credits. This course develops the theory essential to understanding the algorithms that are increasingly found in modern signal processing applications, such as speech, image processing, digital radio and audio, statistical and adaptive systems. Topics include: analysis of nonstationary signals, transform techniques, Wiener filters, Kalman filters, multirate systems and filter banks, hardware implementation and simulation of filters, and applications of multirate signal processing. Matlab will be used extensively.

BME 738 INFORMATION TECHNOLOGY IN MEDICINE
(3-0) 3 credits. Software techniques used in medical treatment and diagnosis, including transform techniques. Medical reference software engineering. Data mining. Hardware and connectivity issues. Bioinformatics.

BME 745 MOLECULAR MACHINES
(3-0) 3 credits. This course studies forces that determine molecular structure, transport, and diffusion, macromolecular assemblies, protein synthesis, structural biology, molecular genetics, enzymology.

BME 746 BIOMIMETICS
(3-0) 3 credits. This course will survey recent research at the intersection of biology and mechanical/structural engineering, in particular, applications where nature’s design philosophies are applied in human-engineered structures. Multi-functional materials, hierarchical design, adaptive materials within closed loop systems, self-healing of natural structures, with a view to self-healing human engineered structures. Applications in aerospace and rehabilitation engineering.

BME 790 SEMINAR
(1-0) 1 credits. May not be repeated for degree credit. Preparation, oral and/or written presentation, and group discussion of a research problem. The student is expected to present orally the results of his/her own research. This presentation normally will directly precede the final defense of the thesis. Enrollment is generally limited to fewer than 20 students.

BME 896 FIELD EXPERIENCE
(0-1) 1 credits. Students will spend a minimum of 3 hours per week in a hospital or another program-approved health care facility. They will observe and/or work with the technical and clinical staff in order to develop insights into the health care profession and the role of engineering in medicine as it applies to their focus area of study and research. Required of doctoral students only.

BME 792 TOPICS
1 to 4 credits. Lecture course or seminar on a topic or field of special interest, as determined by the instructor.

BME 736 ADVANCED FINITE ELEMENT METHODS
(3-0) 3 credits. Variational and weighted residual approach to finite element equations. Emphasis on two- and three-dimensional problems in solid mechanics. Isoparametric element formulations, higher order elements, numerical integration, imposition of constraints, convergence, and other more advanced topics. Introduction to geometric and material nonlinearities. Introduction to the solution of dynamic problems and time integration. Use of finite element computer programs.

BME 606 OCCUPATIONAL BIOMECHANICS
(3-0) 3 credits. Anatomical and physiological concepts are introduced to understand and predict human motor capabilities, with particular emphasis on the evaluation and design of manual activities in various occupations. Quantitative models are developed to explain muscle strength performance; cumulative and acute musculoskeletal injury; physical fatigue; and human motion control.

BME 607 BIOMECHANICS
(3-0) 3 credits. This course presents and introduction to biomechanics from a continuum mechanics perspective. It covers fundamental concepts of solid and fluid mechanics with applications to living systems. Topics in biosolid mechanics include stress, strain, constitutive relations, equilibrium, response to basic loading modes (extension, bending, and torsion), and buckling. Topics in biofluid mechanics include motion of a continuum, constitutive relations, fundamental balance relations, control volume and semi-empirical methods.

BME 673 APPLIED ENGINEERING ANALYSIS I

BME 751 DRUG DELIVERY

BME 603 MOLECULAR BIOLOGY FOR ENGINEERS
(3-0) 3 credits. This course is designed to provide a basic knowledge on molecular biology and bioinformatics that is directly applicable to engineering and related science fields. Up-to-date techniques in genetic engineering biotechnology, and bioinformatics will be introduced for the understanding of biological problems using engineering concepts or engineering/mechanical problems through biological tools.

BME 898 DISSERTATION
Credit to be arranged; not to exceed 30 credits toward fulfillment of Ph.D. degree requirements. Open only to doctoral candidates. Supervised original research investigation of a selected problem, with emphasis on independent work, culminating in an acceptable dissertation. Oral defense of dissertation and research findings are required.

BME 730 VASCULAR MECHANIC/PATHOLOGY

BME 773 Applied Engineering Analysis II

BME 528/528L APPLIED FINITE ELEMENT ANALYSIS

Contact: South Dakota School of Mines and Technology
http://www.hpcnet.org/sdsmt/directory/courses/bme